U.S. warns of muscle harm when heart drugs combined

reuters.co.uk     08-Aug-2008            

WASHINGTON (Reuters) - U.S. health officials warned the public on Friday about the risk of a rare type of muscle injury seen when the cholesterol drug simvastatin is combined with the anti-arrhythmia medicine amiodarone. The Food and Drug Administration said it continued to receive reports of rhabdomyolysis, a type of muscle injury that can lead to kidney failure or death, despite a 2002 warning about combining the drugs. Simvastatin is an ingredient in Merck & Co's Zocor and Abbott Laboratories Inc's Simcor, and is sold generically. It also is one of two components in Merck and Schering-Plough Corp's Vytorin. Amiodarone is an ingredient in Wyeth's Cordarone and is also sold generically. (Reporting by Lisa Richwine, editing by Gerald E.... [read full story]                    

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